Clinical trials may guide you to a healthier, cholesterol-lowering lifestyle

Posted on Fri, 10 Feb 2017 

Do you know what your cholesterol levels are?

High cholesterol levels are a risk factor for the development of cardiovascular disease (CVD) along with obesity, smoking, hypertension, low physical activity levels, and a family history of heart disease. According to Statistics Canada, roughly 40% of Canadians aged 20-79 have high total blood cholesterol levels. Further, the 40-59 age group was found to be at the highest risk of unhealthy cholesterol levels with 43% of Canadians in this group having high blood cholesterol values.

As cholesterol levels are thought to be heavily influenced by the quality of the diet, this represents a largely manageable risk factor. Which begs the question, do you know what your cholesterol levels are?

Cholesterol is an integral part of the human body. Due to the nature of cholesterol and the manner in which it is transported through the body, this substance can be categorized into ‘good’ and ‘bad’ depending on the protein it is attached to in circulation. The balance between good and bad cholesterol is critical for cardiovascular health. Imbalance in this ratio is associated with plaque formation that can lead to obstructed blood flow causing angina, heart attack or stroke.

Elevated bad cholesterol is a risk factor for the development of cardiovascular disease. Scientists have shown that lowering bad cholesterol just 1% can translate into improved heart health and a reduced risk of disease.

The good news is that high cholesterol levels can be combatted with lifestyle changes including eating a healthy diet, increased physical activity, quitting smoking, and adherence to lipid lowering therapies. Traditionally, statins have been the drug of choice for the management of cholesterol. However, scientists studying statins have shown that prolonged use of a high dose can have detrimental effects on muscle and liver function as well as glucose homeostasis. Thus, seeking natural ingredients that can complement cholesterol lowering therapies has been an active area of interest in the field of nutrition for some time. Research into natural ingredients for blood cholesterol lowering is vast and has been realized on the marketplace in the form of many functional food and nutraceutical products.

Currently at KGK Clinical Trial Centers we are investigating a novel probiotic supplement that in previous research has been identified in lowering blood cholesterol and improving heart health. Becoming a participant at KGK Clinical Trials Centre can help you determine your levels of total cholesterol as well as good and bad cholesterol since a complete blood cholesterol assessment is included as part of all our studies. This test is performed by a trained phlebotomist and reviewed by an MD, meaning you can be confident in the results.

KGK Synergize Inc. in London, offering expert assistance and advice through human clinical trials since 1997, is currently conducting a clinical research study to evaluate the effectiveness of an investigational probiotic supplement to lower blood cholesterol. KGK’s clinical trials are conducted under the direction of a Medical Director and Principal Investigator. All studies are reviewed by an independent ethics review board, Health Canada and follow Good Clinical Practice. We are currently looking for participants who would be interested in being a part of this exciting new research.

All records relating to your identity and study participation are confidential as required by the Personal Information Protection and Electronic Documents Act. Each study has its own guidelines – eligibility criteria. To ensure the strongest results, researchers want study participants to be alike in key ways. Examples of eligibility criteria for a treatment trial might be age, gender, weight/height ratio and/or your previous medical history.

To participate in KGK Clinical Trial Centers’ clinical research on this probiotic, you must be 20 to 75 years old (male or female); have elevated blood cholesterol levels; and not currently taking statin medications. Additional information will be determined upon telephone screening. There are no out-of-pocket expenses for you to join this clinical trial, other than your travel expenses to and from the clinic site, parking at One London Place will be validated, and participants will be compensated up to $675 for their time. 


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