Digestive Health: Benefits of Achieving Microbiome Balance

Posted on Thu, 11 Jan 2018  Comments: 1

Attention has never been higher on the type of bacteria that is present and growing inside our digestive tract and the impact it has on our health.  As state of the art research continues to strengthen our understanding of the important roles beneficial bacterial have within our bodies healthy people are asking how probiotics can benefit them.  The focus on probiotics, microorganisms in our gut that include bacteria and yeast, has seen a corresponding increase in the wave of products coming into the market in the form of yogurts, supplements and food.  We are just starting to understand the full range of health impacts these tiny organisms provide to our overall health and well being.  Improving our digestive health is now more important than ever.

As far back as in the 17th century Hippocrates said, “all disease starts in the gut” and current research is uncovering that this indeed is true.  Each of us has a small living community of microbiota (bacteria) living within our gut totaling 39 trillion of these microbes versus only 30 trillion human cells in our entire body.  These small organisms form a small universe called the microbiome.

In humans we have only 20,000 human genes, but there are over 2 million microbial genes in comparison! Research has shown that our gut microbiomes is unique to each person and influences their gut health, oral health, brain health (cognition), blood lipids, immune system and quality of life.  In a healthy gut there are more good or beneficial bacteria than harmful ones, but during stress, sickness or when we take some medications this delicate balance can change causing a disruption of the gut microbiome.  We can increase our good bacteria by taking Probiotics which will improve or add to the beneficial bacteria normally present in the gastrointestinal tract.

Online Constipation Survey

Frequently asked questions such as: is there a single probiotic strain that is most effective; when should you be taking a probiotic; and how can you be sure that a probiotic is working are a few of the questions that researchers around the world are racing to answer. 

What we do know is that promoting a healthy microbiome in your gut leads to healthy outcomes not only in people with obesity and constipation but also in already healthy populations of people. What we do know about probiotics is that each of us has a different and individual composition of beneficial bacteria in our digestive tract that is completely unique to us.  Better intestinal health starts with an understanding of which beneficial bacteria are currently in our gut and what the ratio of helpful to harmful bacteria is.

In research we are examining how to boost the natural production of good bacteria in the gut to enhance digestion, improve bowel regularity and maximize intestinal health.  Relief of mild constipation is often the ideal outcome people seek for taking probiotics, but other lesser known benefits include the potential in helping to regulate your mental health as researchers at McMaster University discovered and published last year.  It is estimated that up to 90% of some neurotransmitters are produced in the gut and specific strains of probiotics are being identified that assist in improving depression in adult populations.

A connection between your gut and your brain? It seems surreal but the benefits of enhanced digestion are showing positive impacts on many systems in the body including cardiovascular health, obesity, depression & mood, along with symptoms of inflammatory and irritable bowel conditions.

KGK Science is currently conducting a clinical research study in London to evaluate the effects of a multi-strain probiotic blend on digestive health in healthy men and women ages 18 to 64.   Along with additional probiotic studies KGK hopes to analyze the results in a healthy population to better understand which bacteria are helping the most.

As a participant you will have the satisfaction of knowing that you are advancing the health of not only yourself but contributing to meaningful research that will impact millions of others

We are currently looking for participants who are interested in taking part in this new research.  All records relating to your identity and study participation are confidential under the Personal Information Protection and Electronic Documents Act.

KGK’s clinical trials are conducted under the direction of a Medical Director and Principal Investigator. All studies are reviewed by an independent ethics review board, follow Good Clinical Practice, and are approved by Health Canada and an Ethics Board.

Each study has its own guidelines and eligibility criteria. To ensure the strongest results, researchers want study participants to be alike in key ways. Examples of eligibility criteria for a treatment trial might be age, gender, weight, height, and/or your previous medical history.

Additional information will be determined upon telephone or online screening. There are no out-of-pocket expenses for you to join this clinical trial. Parking at One London Place will be validated, or bus fare provided, and participants will be compensated up to $600 for their time.

To enroll those interested in participating can complete our online screening questions, call 519-858-8359 or E-Mail Us

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  • Robert Scotland

    By Robert Scotland Mon, 04 Jun 2018

    I am going through what you have discussed here
    Although I am in an older age class (79) it maybe be of benefit to the clinic to look into testing people who are in an older bracket
    As we are living longer at this juncture or stage of life my feeling is your clinic would benefit from a wider audience
    Thank you for the opportunity to participate in this discussion and I hope your clinic sees this and all would benefit