Measuring Physical Activity in Healthy Adults

Posted on Mon, 20 Aug 2018 

by: Michael J. E. Greff, MD

The increased presence of overweight and obese adults in North America can be attributed to low physical activity levels (sedentary behaviour), changes in diet, and nutritional habits with the consumption of foods that are both high in dietary fat and sugars.  As a consequence of increased weight our metabolic and mitochondrial function changes along with muscle function and a decline in physical performance and endurance as you enter middle age (40-65). 

Muscle health is essential in the fight to preserve metabolic health and physical fitness against frailty as we age. Once we reach our golden years muscle mass in our bodies may decrease and can not be restored. Decline in muscle and mitochondrial function is a long term gradual process driven possibly by multiple factors including: physical activity (active versus sedentary lifestyle), diet and chronic conditions.

Over time our mitochondria, the power-plants of our cells, decrease their output.  As their function changes our muscle function and physical performance subsequently declines, even more rapidly in overweight middle-aged people. To restore this energy imbalance regular exercise and proper nutrition remain two of the few options to improve metabolic and mitochondrial function to restore both energy imbalance and muscle function.

Many nutritional products have emerged with enriched formulas of essential minerals, vitamins, trace elements, proteins, and essential amino acids.  Many protein products on the market have an important role in building tissue by supporting repair after injury and regular maintenance of the body.  Unfortunately, these products do not contain ingredients that specifically target mitochondrial function or the loss of muscle function.

At KGK we are conducting a clinical research study to evaluate the ability of Urolithin A to improve muscle health. We are interested in assessing the ability of this supplement to achieve optimal health by repairing faulty and dysfunctional mitochondria. Urolithin A is a compound produced naturally in the intestinal tract following ingestion of pomegranate, berries, and nuts. The is currently no effective treatment for age related decline in muscle function in the elderly. Urolithin A has the potential mitigate the progression of decreasing muscle function.

When you participate in one of our studies you’re taking part in cutting edge nutrition research monitored by medical doctors. Throughout our studies we take steps to ensure participants are treated with the utmost levels of respect and confidentiality. For scientific purposes each study has its own set of eligibility criteria such as age, gender, weight, height, and/or your previous medical history.

KGK is currently seeking participants who are interested in taking part in this new research. For this study our ideal candidate is someone who currently lives a rather sedentary lifestyle (walks less than 30 minutes a day) and wishes to improve their muscle function while also gaining more energy and physical endurance. Participants can be male or female, must be between the ages of 40-65, and available for a study period of 120 days (4 months) with 11 visits.

Additional study information will be determined upon telephone or online screening. During your study visits parking at One London Place will be validated, or bus fare provided. Participants will be compensated up to $1,000 for their time.

If you are interested in participating in this study you can complete our taking our online Physical Activity Survey at www.surveymonkey.com/r/physicalactivityKGK, calling 519-858-8359, or emailing participate@kgkscience.com to have the link sent to your inbox.

KGK, Ontario’s premier research firm based in London, measures outcomes of new natural health products on healthy people throughout Southwestern Ontario.

KGK is also conducting clinical research surveys for healthy adults between the ages of 18-75 on four (4) separate areas; Physical Activity, Sleep/Insomnia, Knee Pain and Cannabis.  Our physical activity survey is intended to assist our doctors and researchers with providing one of the first baselines of healthy people in Canada by measuring their physical activity and sedentary behaviors. 

Participants who complete our surveys are entered into regular draws for Amazon Gift Cards valued at $100.

KGK is also recruiting for studies to evaluate the effect of natural health products to improve cholesterol, blood pressure, immune function, muscle health, digestive health, stress markers, and weight loss. We also have many studies coming soon including: omega-3 fatty acids, and cannabis. For more information visit www.kgkscience.com.

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